The Arizona Cardinals released punter Pat O’Donnell, who had been filling in over the last five games with Blake Gillikin on injured reserve.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

Nolen in three games has put up fine numbers, eight tackles, four tackles for loss, three quarterback hits and one sack, but more importantly he has been a menace creating pressures from the interior.

Oct 6, 2024; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) gestures after a catch against the Arizona Cardinals during the fourth quarter at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images / Darren Yamashita-Imagn Images

Arizona Cardinals head coach Jonathan Gannon says talk of him being on the 'hot seat' as far as his job comes with being an NFL head coach.

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host Cardinals (3-7).

The San Francisco 49ers finished their Week 11 contest with a 41-22 win over the Arizona Cardinals at State Farm Stadium.

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) Sunday in Week 11. Kickoff from State Farm Stadium in Glendale, Arizona, is at 4:05 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the 49ers vs. Cardinals odds and make our expert NFL picks and predictions for the best bets.

Former Arizona Cardinals safety Tyrann Mathieu is starting his own podcast. Mathieu, who won a Super Bowl later in his career on top of earning several Pro Bow