Alajuelense travels to BMO Stadium to face LAFC in a CONCACAF Champions Cup matchup.

Philadelphia Union’s Concacaf Champions Cup campaign resumes on the riverfront as the team is set to host leg one of the Round of 16 against Liga MX standouts Club America on Tuesday night at Subaru Park.

CARSON, Calif. (AP) — Mount Pleasant, a team from the Jamaican Premier League, is bracing to be without as many as 10 players on Wednesday when it takes on the LA Galaxy of Major League Soccer in a CONCACAF Champions Cup matchup.

Paul Arriola scored a pair of goals for the Sounders in his first start in a year due to injury, and Seattle earned a 3-0 result over Vancouver Whitecaps FC in the first leg of their Concacaf Champions Cup match.

San Diego FC’s improbable run in the Concacaf Champions Cup continued on Wednesday night. This time, the azul and chrome offered a new degree of difficulty: They beat Toluca of Liga MX 3-2 at Snapdragon Stadium despite playing down a man for most of the match