Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

The 49ers did allow the Cardinals offense to be on the field for 82 plays, and Jacoby Brissett did pass for 452 yards, but that was partially because San Francisco had multiple shorter fields from the turnovers, and Arizona was playing from behind all day.

He’s such an irreplaceable figure in the locker room and one of, if not the greatest tight end ever to wear the red and gold.

The San Francisco 49ers and Arizona Cardinals face off in Week 11 of the NFL today. Here's where to watch and start time

Learn which TV channel or how to live stream the NFL Week 11 Arizona Cardinals and San Francisco 49ers game, Sunday, Nov. 16.

The NFL season continues in Week 11 when the San Francisco 49ers host the Arizona Cardinals on Sunday. Start time, how to watch, streaming and NFL schedule.

A big stretch of games begins for the San Francisco 49ers on Sunday in Arizona against the Cardinals. Here's how to watch their Week 11 showdown.

The San Francisco 49ers face the Arizona Cardinals in Week 11 of the NFL season on Sunday at State Farm Stadium.

Arizona Cardinals vs San Francisco 49ers picks, predictions, odds, win probabilities for NFL Week 11 Sunday game on Nov. 16. Who will win game today?

Kickoff from State Farm Stadium is set for 4:25 p.m. ET on FOX. The 49ers are 3.5-point favorites, according to the latest 49ers vs. Cardinals odds. The over/under for total points scored is 48.5. Before making any 49ers vs. Cardinals picks, make sure you check out the NFL picks from the SportsLine Projection Model.

Former Pro Bowl RB LeSean McCoy believes the Arizona Cardinals point shaved in their Week 11 loss to the San Francisco 49ers.