The San Francisco 49ers dropped to 6-4 on the season after a 42-26 Week 10 loss to the Los Angeles Rams at Levi's Stadium in Santa Clara, California. Below are several statistics and notes from Sunday's game, which were provided by the 49ers Communications staff. Mac...

Watch the best plays by the Los Angeles Rams against the San Francisco 49ers in Week 10 of the 2025 NFL season.

The San Francisco 49ers finished their Week 10 contest with a 42-26 loss against the Los Angeles Rams at Levi's® Stadium.

The NFC West is loaded at the top, and two of the division's contenders meet on Sunday when the 6-3 San Francisco 49ers host the 6-2 Los Angeles Rams. This is the second meeting between these two rivals, as the 49ers won the Week 5 matchup 26-23 in overtime on Thursday Night Football.

Los Angeles Rams running back Blake Corum rushes for 15 yards against the San Francisco 49ers at Levi's Stadium.