DEAR DR. ROACH: I’m an 88-year-old female who has been diagnosed with ventricular fibrillation. My cardiac electrophysiology doctor, who implanted a conventional pacemaker four years ago, has noticed ...

The carving up of the amyloid precursor protein (APP) by the successive action of β- and γ-secretases liberates Aβ, but also yields a small intracellular fragment, the APP intracellular domain (AICD).

When the amyloid precursor protein (APP) gets chopped up to make Aβ, other fragments are released, including APP’s intracellular domain. Scientists believe AICD acts as a transcription factor, though ...

Dear Dr. Roach: I’m an 88-year-old female who has been diagnosed with ventricular fibrillation. My cardiac electrophysiology doctor, who implanted a conventional pacemaker four years ago, has noticed ...