One of the most widely used chemotherapeutic agents for colorectal cancer is 5-fluorouracil (5-FU), a cornerstone treatment ...

Apoptosis is a process in which cells die off, intentionally. This programmed cell death pathway helps eliminate billions of cells every day, most of which are blood or gut cells, so they can be ...

A new research paper was published in Volume 17 of Oncotarget on June 3, 2026, titled "The anticancer effects of PCAIs in ...

Figure 10: Biochemical effects of PCAIs on cancer cells. PCAIs-treated cancer cells show the depletion of the monomeric G-proteins RAC1 and RHOA. MAPK and PI3K/AKT signaling pathways are activated ...

An AI-assisted drug discovery platform using transfer learning has identified a promising gp130 inhibitor for colorectal ...