“Estimates show approximately 100,000 people are affected by ATTR amyloidosis across Europe, most with cardiomyopathy, so this approval marks a critical step toward addressing this underserved patient ...
This rare condition can’t be cured, but its symptoms can be treated. Take this assessment to learn what more you can do to manage the condition. Before you were diagnosed with transthyretin ...
Claims-based analysis showed 64% of patients received ATTR-CM diagnosis ≥6 months after incident HF, with median delays ...
ATTR-CM is a heterogeneous and rapidly progressive disease, and patients often present with complex clinical profiles. At Heart Failure 2026, Alnylam will present multiple new analyses from the Phase ...
ATTR phenotypes vary by genotype as well as by gene penetrance, age, and geographic location. A new analysis examined data from untreated, symptomatic patients who had 1 of 4 variants: F64L, I68L, ...
Treatment with vutrisiran led to a statistically significant reduction in the composite of all-cause mortality and recurrent CV events vs placebo. Treatment with vutrisiran was associated with a ...
It can be tough to share the news of a genetic health condition, but doing so empowers your relatives to take charge of their health. ATTR occurs when the protein transthyretin (TTR), which is made in ...
Credit: Getty Images. The sNDA is supported by data from the phase 3, placebo-controlled APOLLO-B study. The Food and Drug Administration (FDA) has accepted for review the supplemental New Drug ...
Caring for someone with ATTR amyloidosis can be physically and emotionally demanding. To reduce the chances of burnout, caregivers should also prioritize their own well-being. Factors such as ...
Please provide your email address to receive an email when new articles are posted on . Vutrisiran lowered risk for death and recurrent CV events vs. placebo in patients with ATTR-CM. The results were ...
"ATTR amyloidosis was characterized by distinct patterns of functional impairment across all disease phenotypes, attributable to multiple physiological mechanisms. Multiple CPET parameters were ...
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