Base excision repair (BER) is a fundamental pathway that safeguards genomic integrity by detecting and removing small base lesions arising from oxidation, alkylation, deamination or spontaneous base ...
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma: CALGB 500104 No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2006 ASCO ...
A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by ...
Fluorescence-guided tumor resection using a telomerase-dependent adenoviral GFP for cancer-specific labeling. Background: MX, the first base excision repair (BER) inhibitor evaluated in humans, blocks ...
This study is led by Shaorong Gao (the Dean of School of Life Sciences and Technology and the Director of the Frontier Science Center for Stem Cell Research, Tongji University), Shuai Gao (National ...
DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit ...
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