CRISPR gene editing has transitioned from a laboratory curiosity to a cornerstone of modern biotechnology, revolutionizing our approach to genetic diseases, including Charcot-Marie-Tooth (CMT) disease ...

For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the most frustrating bottlenecks in gene therapy has been deceptively simple: the ...

Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Investigators have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations. The system can be formulated completely as ...

Scientists have developed a novel gene editing tool that could have vast implications for research and therapeutics. This technology is called STITCHR (site-specific target-primed insertion through ...

When activated by its target, the newly characterized molecule rips the genome apart, a lethal move that researchers can ...

CRISPR has taken the bioengineering world by storm since its first introduction. From treating sickle cell diseases to creating disease-resistant crops, the technology continues to boast success on ...

Senior Correspondent Gene therapy has always held enormous promise to correct genetic diseases, but turning that potential into treatments has been challenging. In a study published May 15 in the New ...

A research team led by geneticist Jeannie Lee at Harvard Medical School, cell biologist Jeanne Lawrence at UMass Chan Medical School, and molecular biologist Jun Jiang has used a refined version of ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement. A new paper by investigators from Mass General Brigham ...

At the WIRED Health summit last week, Harvard biochemist and gene-editing pioneer David Liu said that later this year his lab plans to report on a single gene-editing strategy that could treat many ...