Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death globally, with incidence continuing to rise in many regions. Despite advances in ...

The ethics of using safe gene therapies to improve the health and cognition of Down syndrome children and adults.

Functional genomics is central to modern drug discovery, yet high attrition rates persist. In this article, Dr Salman ...

I was born in Washington, DC, in 1964, the oldest of three sisters, but the place that truly formed me as a scientist was Hilo, on the Big Island of Hawaii. Growing up there, far from the mainland ...

In research published today in Nucleic Acid Research, co-first author Seong Guk Park, PhD, and corresponding author Elizabeth Kellogg, PhD, St. Jude Department of Structural Biology, designed a ...

CRISPR-based therapy is a transformative approach to medicine that allows for targeted changes to the genome by directly addressing the source of disease, or to the epigenome through silencing of ...

Intellia Therapeutics, a leading biotechnology company, announced that its CRISPR-based treatment for a rare swelling ...