BALTIMORE — An ambitious effort to cure HIV with CRISPR genome editing fell short in an early clinical trial, investigators announced Friday morning. In the study, run by Excision BioTherapeutics, ...

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched. The technology has largely been tested in cells ...

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This week's episode includes an update from AACR, HIV CRISPR screen mapping, tissue engineering in the liver, and cancer business news.

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Excision BioTherapeutics has so far released positive safety data from the first 3 participants living with HIV-1, with no evidence of vector shedding in sexual organ tissue. A cure for HIV-1 becomes ...

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while ...

Credit: Getty Images Thanks to antiretroviral drugs, HIV diagnosis can be managed, as science is getting closer to finding a cure. The Conversation — HIV, the virus that causes AIDS, was first ...

How does HIV, armed with only nine genes, manage to hijack the immune system so effectively? For decades, researchers have known that the virus depends on human proteins to enter, replicate, and ...

A proof-of-principle study published in Nature Materials shows that gold nanoparticles loaded with CRISPR and other gene-editing tools safely and effectively edited blood stem cells. (Photos, diagram ...

When activated by its target, the newly characterized molecule rips the genome apart, a lethal move that researchers can ...