A review in Molecular Biology Reports describes how pro-inflammatory forms of regulated cell death, including ferroptosis, ...

Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms. The building blocks required ...

Study offers new ways to understand cancer and its vulnerabilities, and suggests that certain protein inhibitors could potentially be effective treatments for the disease Boston, MA—Metastatic ...

Cells can die naturally from age or disease, but organisms can also actively trigger the death of certain cells when needed. This is known as programmed cell death (PCD), a central biological system ...

Cells depend on cysteine, but excess free cysteine comes at a price. Nakamura et al. show that excess cysteine disrupts mitochondrial iron homeostasis, which drives a distinct iron-dependent cell ...

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their ...

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's. The team at WEHI, including ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed. Aging cells secrete substances known to ...

When cells are about to die, they send signals that trigger proteins which are supposed to destroy them, but it doesn’t always happen that way. Some cells activate the signal but then resist the ...

Photoreceptors are specialized cells in the eye that convert light energy into neural signals. Several diseases that cause irreversible vision loss, including age-related macular degeneration, ...

Researchers identified molecular switches that push cancer cells into senescence and evade chemotherapy, offering potential ...