Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

The Warburg effect describes how cancer cells switch from oxidative phosphorylation to glycolysis even in oxygen-rich ...

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

Your liver cells are forgetting how to do their jobs under dietary stress. Here's how that signals cancer risk years before tumors appear.

Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel ...

Drug developers are racing to design molecules that coax our cells into burning more energy even when we are sitting still, ...