The cerebellum, a major structure in the human hindbrain, is known to be of central importance for enabling several motor functions, along with cognition, emotional regulation and language processing.

Scientists at the University of Southern California (USC) have developed an organoid model of the human brain that generates granule cells and Purkinje neurons—two major cell types found in the human ...

Researchers use zebrafish models to discover that the RLS risk gene MEIS1 regulates Purkinje cell survival and motor control.

The image shows how the cerebellum (white) send its projections across the brain of a newborn mouse. A wide network of color-coded axons reveals how this tiny structure connects with multiple brain ...

An irresistible urge to move the legs or other areas, often accompanied by unpleasant sensations at night or during rest: Restless Legs Syndrome (RLS) affects millions of people worldwide. Despite ...

The evolution of higher cognitive functions in humans has so far mostly been linked to the expansion of the neocortex. Researchers are increasingly realizing, however, that the 'little brain' or ...

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model ...

The mammalian cerebellum is key to motor control and contributes to many of the higher brain functions. Scientists have now decoded the genetic programs that control the development of cerebellar cell ...

Cerebellum seen here in orange. Cerebellar means "relating to the cerebellum." Cerebro-cerebellar circuits connect the cerebrum and cerebellum. Source: SciePro/Shutterstock A pioneering new study ...

Genetic maps of the development of cells in the cerebella of human, mouse and opossum shed light on ancestral and species-specific cellular and molecular characteristics of cerebellum development. The ...