A new research paper titled "Development of a DNA damage-induced senescence model in osteoarthritic chondrocytes" has been published in Aging. Senescent cells (SnCs) have been described to accumulate ...

15-Lipoxygenase-1 (15-LO-1) is involved in many pathological processes. The purpose of this study was to determine the potential role of 15-LO-1 in osteoarthritis (OA). The levels of 15-LO-1 ...

ACI and MACI treatments could be improvised with the first of its kind feat by Edogawa Hospital, Tokyo TOKYO--(BUSINESS WIRE)--Regenerative therapy to treat knee joint damages gets a boost with a ...

A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging. While advanced age is widely ...

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA). However, the ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...

Researchers have generated photosynthetic mammalian cells by transplanting essential components of plant-derived chloroplasts into chondrocytes. When transplanted into degenerating chondrocytes in ...

Scientists at Stanford Medicine have discovered a treatment that can reverse cartilage loss in aging joints and even prevent arthritis after knee injuries. By blocking a protein linked to aging, the ...

(A) UMAP visualization of the 13,363 chondrocytes from healthy human cartilage. Color represents the chondrocyte subset. (B) UMAP visualization of the expression of representative marker genes for ...