Scientists at the Montreal Clinical Research Institute (IRCM), led by Université de Montréal medical professor Javier Di Noia, have shed light on a fundamental mystery in immunology: How do immune ...

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a new study from Duke University. The findings, published in PLOS Biology, ...

Some cases of the most common childhood cancer, B-cell acute lymphoblastic leukemia (B-ALL), return after treatment—and ...

Every cell carries a molecular record of time. As DNA is copied, repaired and exposed to damage, mutations gradually accumulate — most harmless, some potentially consequential. A new Cell study found ...

As in a batch of kombucha or a barrel of sherry, microbes can assemble into a mat-like layer at the boundary between air and liquid. In laboratory culture, the bacterium Pseudomonas fluorescens SBW25 ...

Mutations found in roughly 20% of human cancers may promote tumor growth by changing how DNA is organized inside cells.

A missense mutation in the sheep MC4R gene, enriched in year-round estrus breeds, boosted receptor signaling and ...

In simple terms: a mutation is a stable change in genetic sequence that can be copied when cells or viruses replicate. Most mutations have no detectable effect, some contribute to disease, and a small ...

Nearly every cell in the human body contains essentially the same genetic information, yet different cells activate different ...

Researchers have refined a powerful DNA sequencing tool that can uncover hidden mutations that occur naturally in our bodies as we age. In the largest study to date, they have used the tool to provide ...

Mutations found in about 20% of human cancers may promote malignant growth through a shared change in how DNA is organized, ...