Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in membrane remodelling, has a critical role in endocytic membrane fission events. The use of complementary ...

Dynamin-related proteins (DRPs) are multi-domain GTPases that function via oligomerization and GTP-dependent conformational changes to play central roles in regulating membrane structure across ...

Dynamin is a protein that plays a central role in endocytosis—the process where cells internalize substances by wrapping them in cell membrane vesicles. For a vesicle to detach, the neck of the ...

Researchers have determined the molecular structure of dynamin -- a "wire-puller" that mediates nutrient uptake into the cell. Since pathogens such as HIV can also enter the body's cells in this way, ...

This article provides an introduction to dynamin and endocytosis and lists the inhibitors that are relevant to research. Dynamin is an important GTPase enzyme that takes part in different endocytotic ...

In a world first, neuroscientists at Flinders University have identified a series of chemical tools that can either increase or inhibit the release of neurotransmitters by neurons, the cells of the ...

An unexpected finding on how nerve cells signal to one another could rewrite the textbooks on neuroscience, says a collaborative team of researchers at Weill Cornell Medical College and Yale ...

Dr. Katja Falber and Professor Oliver Daumke, structural biologists at the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch, together with researchers from Freie Universität (FU) Berlin, ...

Dynamin assembles into a ring around the neck of a forming vesicle and utilizes GTP hydrolysis energy to constrict and sever the membrane. The simulation reveals that the dynamin ring expands (loosens ...

Dr. Katja Fälber and Professor Oliver Daumke, structural biologists at the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, together with researchers from Freie Universität (FU) Berlin, ...