HIV-1 Vpu triggers the cleavage of TDP-43 by stimulating Caspase 3 activation. The cleavage products generated can induce the ...
To investigate this, they used lethally irradiated wild-type mouse embryonic fibroblasts (MEFs) and MEFs deficient in caspase 3 and caspase 7, which are essential apoptotic proteases, as models of ...
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
For example, researchers will measure cell death to determine a drug’s anticancer effectiveness. Scientists commonly use caspase assays to evaluate apoptosis, evaluating caspase activation—a hallmark ...
Dissecting caspase-2-mediated cell death: From intrinsic PIDDosome activation to chemical modulation
Caspase-2, an initiator caspase, plays a critical role in programmed cell death in response to certain cellular stresses. Its activation is facilitated by the PIDDosome, a multi-protein complex ...
Age-related changes in the fibroblasts, cells that create the skin's structure, contribute to the development of aggressive, ...
The patent details methods of generating three-dimensional organoids capable of giving rise to hematopoietic cells, including precursors, and/or immune cells. This includes cells such as T cells, B ...
New adventure. New rival. Check out the Sonic The Hedgehog 3 trailer for the upcoming movie starring Jim Carrey, Ben Schwartz, James Marsden, Tika Sumpter, Idris Elba, Colleen O’Shaughnessey ...
The Apple Watch Series 3 improved upon its predecessors with upgraded components and a model with a cellular connection. The Apple Watch Series 3 is still for sale in 2022, nearly 5 years after ...
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