The American Journal of Managed Care

Bepirovirsen for Chronic Hepatitis B Receives Breakthrough Therapy Designation, Priority Review

FDA regulatory momentum includes priority review and breakthrough therapy designation for a potential first-in-class CHB ...
BioWorld

IFNα-like small molecules successfully inhibit HBV replication

It’s known that interferon-alpha (IFNα) activates interferon-stimulated genes (ISGs) and disrupts the hepatitis B virus (HBV) replication cycle. Pegylated (PEG)-IFNα has been widely used for its ...
EurekAlert!

New clues to hepatitis B species restriction could help build a novel model for studying infection and testing therapies

More than 250 million people worldwide live with chronic hepatitis B (HBV), yet there is still no accessible animal model for studying the disease or testing novel therapies. Researchers have now ...
EurekAlert!

Paclitaxel-induced immune dysfunction and activation of transcription factor AP-1 facilitate Hepatitis B virus replication

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy. Paclitaxel (PTX) treatment has been identified as a ...