Measuring splicing and chromatin accessibility simultaneously in frozen tissues remains challenging. Here we combined single-cell isoform RNA sequencing and assay for transposase accessible chromatin ...
Scientists at ETH Zurich have broken new ground by generating over 400 types of nerve cells from stem cells in the lab, far surpassing previous efforts that produced only a few dozen. By ...
Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cells in the human brain, according to the latest ...
The brain is the most complicated organ in the human body. With billions of cells that create trillions of connections to allow an individual to move, think, and remember, many of its innerworkings ...
To provide definitive evidence that these munsuppresive, macrophage-like leukemia-supporting cells are, in fact, derived from LSCs, we sorted LSCs from two AML patients with the FMS-like tyrosine ...
Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...
Every person walking the planet carries roughly 37 trillion cells, and nearly every one of those cells holds an identical ...
Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...