After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about 0.01 mm in size, it must be tightly folded. DNA wraps around proteins call ...

DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...