A review finds that HIV-1 suppresses MAVS-dependent antiviral signaling in myeloid cells while distinct IFI16 and CARD8 pathways can promote inflammasome activation in other cellular contexts.
A new study reports that the flavonoid trilobatin reduced airway inflammation in a mouse model of asthma by suppressing NLRP3 ...
Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...
In a study published Oct. 19 in Cell, Yale researchers identified a previously unknown mechanism by which a nutrient abundant ...
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