Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Diuretics are agents commonly used in diseases characterized by excess extracellular fluid, including chronic kidney disease, the nephrotic syndrome, cirrhosis and heart failure. Multiple diuretic ...

Big clinical trials of loop diuretics for keeping patients stable after discharge from a heart-failure (HF) hospitalization have been in short supply, so firm guideline recommendations on the matter ...

Thiazide diuretics became available in the late 1950s and were the first effective oral antihypertensive agents with an acceptable side-effect profile. 1,2 A half-century later, thiazides remain ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...

Diuretics are a class of medications commonly known as "water pills." There are several different classes of diuretics, each of which works differently in the kidneys to help rid the body of extra ...