Lysosomes are digestive organelles of the endocytic and autophagic pathways. Increasing lysosome enzyme activities could help to clear pathological cellular waste. A recent study shows that lysosomal ...

The lysosome is a small membrane bound organelle that can be found in most animal cells. It was once thought that these little sacs were like recycling centers that could take up cellular waste ...

An international research team from Bielefeld University and the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has uncovered a previously unknown regulatory mechanism in human cells.

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, ...

Hutchinson-Gilford progeria syndrome (HGPS) is a rare progeroid disorder, featured with premature skin wrinkling, lack of skin elasticity, absence of subcutaneous fat, alopecia, atherosclerosis and ...

I’d love to read a creepy science fiction story where people dissolve. I asked my friend Anders Omsland if that could happen. He’s a biomedical researcher at Washington State University. He told me a ...

If you had to swallow a pouch of toxins, you’d like to be certain the pouch was indestructible. Similarly, every eukaryotic cell seeks to ensure that the membranes of its many miniscule sacs called ...

For the first time, the pathway through which cells repair damaged lysosomes has been observed and described. Lysosomes are the recycling center of a cell, where molecular waste is degraded into the ...

The lysosome was once thought of as the trash can of the cell, a dead-end destination where cellular debris was sent for disposal. But a growing body of research shows that this enzyme-filled vesicle ...

Researchers have discovered that defects in the transport of lysosomes within neurons promote the buildup of protein aggregates in the brains of mice with Alzheimer's disease. The study suggests that ...