Researchers from the University of New Hampshire looked at the developmental process of the cerebral cortex—the outermost layer of the brain—and examined how neurons, or nerve cells, refine their ...

Newborn nerve cells must squeeze through crowded, narrow spaces—through dense tissue, past other cells, and between fibers—to reach the areas where they form neural circuits in the brain cortex. In a ...

During brain development, neurons have to migrate long distances through complex environments until they reach their final destination. In order to find guidance, they must establish several ...

To move forward or migrate, the different cells in our body must exert forces or interact with their surrounding environment. Interestingly, however, a fault in these interactions can also be the ...

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4). This protein can guide ...

Breast cancer metastasis to the brain, occurring in about 15–25% of cases, represents a major obstacle in the treatment of triple-negative breast cancer (TNBC). The molecular mechanisms driving this ...

The migration of neural progenitor cells (NPCs) to their final destination during development follows well-defined pathways, such as along blood vessels. Cells originating from the highly malignant ...

Ikoma, Japan—Ever wondered how the different cells in our body communicate with each other to fulfill their different roles—be it cells repairing a tissue injury or immune cells moving towards an ...