Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...

Patients with ovarian clear cell carcinoma (OCCC) whose tumors have specific mutations in the PPP2R1A gene were found to have improved survival following immunotherapy compared to patients without ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Researchers developed a single-cell sequencing method that simultaneously measures cancer-linked DNA mutations and gene activity in solid tissues. Applying the approach to human esophageal samples ...

Results from a retrospective study compared and explored biomarkers associated with outcomes in myelodysplastic syndrome (MDS) with plasma cell neoplasms. MDS is a group of heterogeneous clonal ...

Men with metastatic hormone-sensitive prostate cancer who are carriers of germline mutations have shorter survival compared with noncarriers. Men with metastatic hormone-sensitive prostate cancer ...

In a major step toward treating rare neurological diseases, scientists have used gene editing to correct mutations inside the brain of living mice with a single injection. This new approach, described ...

For patients with an often-deadly form of leukemia, new research suggests that lingering cancer-related mutations - detected after initial treatment with chemotherapy - are associated with an ...

In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for ...

In 1943, a physicist and a biologist published a paper that confirmed one of the central pillars of Darwin's theory of evolution. The paper, by Max Delbrück of Vanderbilt University and Salvador Luria ...