What just happened? What does it mean? What are the pertinent factors (and, perhaps, tiebreakers) prominently in play as each conference's seven-team bracket begins to crystallize? All will be ...

The San Francisco 49ers will go into a vital Monday Night Football matchup vs. the Indianapolis Colts without two starters.

San Francisco 49ers wide receiver Brandon Aiyuk hasn't been on the field this year, but he's been a frequent topic of ...

The Indianapolis Colts released their final injury report ahead of a crucial Monday Night game against the San Francisco ...

The Indianapolis Colts host the San Francisco 49ers on 'Monday Night Football' in NFL Week 16 action: Injury report.

USA Today's NFL experts make their picks for a Week 15 showdown between the San Francisco 49ers and Tennessee Titans ...

The NFL season continues in Week 15 when the San Francisco 49ers host the Tennessee Titans on Sunday. Start time, how to ...

The San Francisco 49ers have a perfect post-Bye Week opener. Not only do they get to play a game at home, but they face ...

The Arizona Cardinals are having one of their worst seasons in recent history, and it is happening when the NFC West might be ...

The 49ers and Rams faced off in the NFC title game in January of 2022 with Los Angeles punching their ticket to the Super ...

The Tennessee Titans will take on the San Francisco 49ers in Week 15 action. Here is one person that could give the Titans a ...