“Pharmacological inhibition of p38 MAPK significantly reduced α-SMA and Col3A1 expression in both TGF-β1-stimulated fibroblasts and primary IPF cells” Led by Shan Zhu — with corresponding author Yan Y ...

Home » BioWorld Science » GSK-3179106 reduces inflammation and acute lung injury in mice through p38 MAPK targeting To read the full story, subscribe or sign in.

Researchers designed a phenylthioether chalcone compound, B15, that directly binds p38 MAPK and reduced inflammation, oxidative stress and lung tissue damage in a mouse model of acute lung injury.

A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung ...