Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers—about a millionth of a milliliter. The cell manages this by ...

Cancer occurs when cells divide uncontrollably and displace healthy cells. Tumor suppressors provide an important defense against this. As molecular growth inhibitors, they prevent healthy cells from ...

The protein p53 is often called the guardian of the genome for its central role in preventing cancer. Yet paradoxically, it is also one of the most frequently mutated and dysfunctional proteins in ...

The protein p53 is often called the guardian of the genome for its central role in preventing cancer. Yet paradoxically, it is also one of the most frequently mutated and dysfunctional proteins in ...

Schematic illustrating the effects of p53C and M237I in driving the conversion of p63C and p73C droplets into amyloid aggregates at physiologically relevant temperatures. Heparin prevents the ...

Can networks of genes be stimulated using resonance? Researchers at the Niels Bohr Institute are investigating whether the protein p53, which activates a range of different genes, can be induced to ...

Researchers engineered hybrid strontium sulfite nanoparticle-modified lipid nanoparticles to deliver p53 mRNA, producing ...

In a recent perspective published in the journal Cell Death and Differentiation, researchers in France, Germany, and Sweden discussed the unique mutational spectrum of the transformation-related ...

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic micrometers-about a millionth of a milliliter. The cell manages this by ...