Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

A study published in Neuropathology and Applied Neurobiology has now found evidence of α-synuclein aggregates — a key pathological hallmark of Parkinson disease (PD) — in the gut and brain in people ...

Age-related disease may be mediated by low levels of chronic inflammation (“inflammaging”). Recent work suggests that gut microbes can contribute to inflammation via degradation of the intestinal ...

Surely, inflammation is half a billion years old, since even the lowly starfish may experience it. Virtually every human being who ever lived has suffered from it, perhaps dozens or hundreds of times.

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING ...