The study is published in the journal National Science Review. The long-overlooked structural feature of the rotary carbonyl rings underpins the ultra-high K + /Na + selectivity, but has never been ...

Ion channels in the nervous system are among the most important targets for insecticides. Understanding the structure of the channels is key for the identification of novel species-specific binding ...

Researchers have discovered a new mechanism for potassium channel inhibitor entry, which could improve the specificity of drugs targeting the channel. Upon binding to calcium ions, BK channels allow ...

Intrigued by the properties of ion channel proteins commonly observed in cells, researchers have developed the first synthetic mechanosensitive potassium channel using a newly developed aromatic ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels—which open only when a specific voltage is reached across the cell ...

Potassium channels are openings that allow charged potassium atoms to cross the cell membrane. Voltage-gated potassium channels — which open only when a specific voltage is reached across the cell ...

Underlying every thought, heartbeat and movement are ion channels, busily conducting high-speed streams of ions into cells, like subway trains coursing through tunnels. Ion channels span the cellular ...

Voltage-gated ion channels control electrical activity in nerve, muscle and many other cell types. The crystal structure of a bacterial voltage-gated channel reveals the astonishingly simple design of ...

Following this design principle, the researchers create angstrom-scale pores in bi-layer graphene sheets, and decorate the two pore edges with twisted rings of carbonyl groups. The artificial ion ...