VCP/p97 uses Ufd1-Npl4 and FAF1 to process polyubiquitylated substrates. Here, the authors show how these adapters coordinate ubiquitin-chain engagement and delivery while adapting to conformational ...
An international team of researchers, including those at the Earth-Life Science Institute (ELSI) at the Institute of Science Tokyo, has developed a protein language model that brings together two ...
On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic mutations, the first step in developing effective therapeutics. Cells become ...
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