Multiple sequence alignment (MSA) is a cornerstone of computational biology, facilitating the exploration of functional, structural and evolutionary relationships among biological sequences.

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

In the beginning, there was Needleman-Wunsch, which begat Smith-Waterman, which begat FASTA, which begat BLAST, and so on. Peel away the information technology jargon surrounding these alignment ...