Researchers have developed 'tomoseqr' -- a new software tool that enables easy estimation of the three-dimensional (3D) spatial distribution of gene expression. Tomoseqr is free to use and has been ...

Co-first author Jiyuan Yang, PhD, St. Jude Department of Computational Biology and co-senior and corresponding author Jiyang Yu, PhD, St. Jude Department of Computational Biology interim chair look at ...

Researchers have created a highly detailed spatial multiomic atlas to date of glioma tumour microenvironments.

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Understanding the composition and architecture of cells within tissues is fundamental to studying tissue function and more broadly, human biology. The complex dynamics of cellular functions and ...

Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to map the 3D organization of the human genome and how it changes over time, ...