Most people recognize Alzheimer's from its devastating symptoms such as memory loss, while new drugs target pathological aspects of disease manifestations, such as plaques of amyloid proteins. Now a ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a ...

Engineers and biologists at Dartmouth College have found that, just like word order affects meaning in a sentence, the placement of genes within a plasmid—known as gene syntax—can influence how ...

Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.

The molecular machinery that normally builds proteins inside cells has now taken on a new role as a "switch." A research team at POSTECH (Pohang University of Science and Technology) has developed a ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...