BioWorld

Discovery of potent tubulin polymerization inhibitor that targets tubulin colchicine-binding site

Discovery of potent tubulin polymerization inhibitor that targets tubulin colchicine-binding site April 4, 2024 ...
ascopubs.org

Phase I dose-ranging, pharmacokinetic (PK) study of tesetaxel, a novel orally active tubulin-binding agent.

Phase IB pharmacokinetic (PK) study of Src kinase inhibitor AZD0530 plus anastrozole in postmenopausal hormone receptor positive (HR+) metastatic breast cancer (MBC). Conclusions: In heavily ...
News Medical

Studying the Dynamics and Function of Microtubules to Understand the Tubulin Code

Microtubules are cell constituents that display several astounding properties and a unique pattern of behavior during the cell cycle. Microtubules are regulated by several proteins and complexes, and ...
BioWorld

Discovery of potent tubulin polymerization inhibitor that targets tubulin colchicine-binding site

Researchers from China Pharmaceutical University published data detailing the discovery and preclinical evaluation of novel tubulin polymerization inhibitors as potential anticancer agents.