It's a fundamental principle of science: Correlation does not equal causation. Every cancer cell has genetic mutations, but ...

The Cancer Gene Census (CGC) is a widely used module within the Catalogue Of Somatic Mutations In Cancer (COSMIC) that comprises an ongoing effort to catalogue and describe all genes with causal ...

Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature ...

In this Innovation Spotlight, Peter Campbell, the cofounder and chief scientific officer of Quotient Therapeutics discusses a new somatic genomics platform built to identify these mutations and ...

A pivotal study has provided unprecedented insights into the genetic architecture of sweet oranges, highlighting the critical role of somatic mutations in shaping fruit development. By constructing a ...

Analysis of Alzheimer’s brains revealed age-related accumulation of cancer driver mutations, particularly in microglia. These ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

Real-world clinical outcomes of patients with metastatic colorectal cancer (mCRC) treated with trifluridine-tipiracil + bevacizumab by performance status.

Genetic disorders can occur due to mutations in one gene (monogenic), multiple genes (multifactorial inheritance), and mutation in one or more chromosomes. Point mutations are where one nucleotide in ...