Researchers have described a large set of previously unrecognized enzymatic domains—named the Lipocone superfamily—and outlined their evolutionary pathway from bacterial defense molecules to key ...

A new review synthesizes the signaling pathways, extracellular matrix cues, metabolic switches and transcription factors that ...

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

Authors: Zhe Ying, PhD, Assistant Professor of Stem Cell Biology and Regenerative Medicine at the Icahn School of Medicine at Mount Sinai; Qiwen Gan, PhD, Postdoctoral Fellow in the Ying Laboratory at ...