Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...
Monocytes, a special type of white blood cell, secrete cytokines as inflammatory messengers that are crucial for an appropriate immune response. Researchers at the University Hospital Bonn (UKB) and ...
In a recent study published in the Journal of Thrombosis and Haemostasis, researchers investigated the role of platelets in the adverse immune response against a coronavirus disease 2019 (COVID-19) ...
Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...
Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...
Biomedical researchers at Case Western Reserve University report that their latest innovation in developing synthetic platelets could help save lives by rapidly stabilizing clots to reduce blood loss ...
Pharmacological Approaches Targeting Neutrophilic Inflammation: Volume II.Neutrophils (or polymorphonuclear leukocytes, ...
Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...
The lives of many cancer patients are saved by the transfusion of platelets, but there is a chronic shortage of these fragile blood-clotting components because of spoilage. A new technique may double ...
For the first time, scientists at University of Leeds reveal a complex mechanism behind blood clotting. The findings, ...
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