The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses. Upon mutation-induced loss of TBK1 function, patients show an ...

The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...

Researchers from the University of Science and Technology of China report the first near-atomic-resolution structure of the human ATR–ATRIP complex bound to clinical inhibitors, providing ...

Human stem cells can differentiate into any human cell. But dedifferentiation, differentiation in reverse, is implicated in several diseases. Now, researchers have uncovered a mechanism key to the ...

One of those genes encodes the enzyme DHDDS, part of the pathway that glycosylates proteins in higher cells. Retinitis pigmentosa from DHDDS mutations is called RP59. This is a recessive genetic ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during gene expression, findings that may inform the ...

Study outcomes include changes nutrient absorption, gastrointestinal symptoms, and bowel function between the enzyme blend and placebo. About BIO-CAT, Inc.

A new study suggests an enzyme unique to Homo sapiens may have made us more competitive water seekers than our closest ...