However, stratified permuted block randomization fails to achieve good overall balance when the number of strata is large, whereas traditional minimization methods also suffer from the potential ...

In summary, DA should be considered a valid alternative to randomisation or allocation via the random permuted blocks method, particularly for small to moderate-sized clinical trials with multiple ...

A permuted-block randomization scheme was used with stratification according to the following: clinical stage at presentation (inoperable breast cancer [tumor stage T4 or nodal stage N2 or N3 and ...

By using permuted-block randomization, participants were assigned to either celecoxib 400 mg by mouth twice daily or matching placebo (both provided by Pfizer, New York, NY) for 4 to 6 weeks before ...

Random assignment (stratified permuted block random assignment type) was generated from a validated computer-generated random assignment schedule. The primary end points were DFS in ITT and tumor ...