This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

An overview of the articles in this Focus issue on therapeutic antibodies. Over the past 10 years, the market for monoclonal antibodies has grown exponentially. This focus issue brings together ...

New phase 2b/3 trial results with MSD's experimental respiratory syncytial virus (RSV) antibody clesrovimab have fired a shot across the bows of AstraZeneca and Sanofi, currently predicting ...

AnkA and Abl-1 are crucial for A. phagocytophilum infection, as depletion of AnkA enzymatic activity by antibody binding or silencing of Abl-1 inhibits pathogen colonization of mammalian cells. [23] ...