CRISPR gene editing could kill HIV. But is it a cure? Gene-cutting technique is targeting infectious disease, hoping to eradicate virus.

Researchers hoped they could send CRISPR to those cells and, by cutting the HIV DNA lurking there at two spots, slice out the virus. In the Phase 1 trial, investigators administered the treatment ...

In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to snip the AIDS-causing virus out of his cells.

The therapy, named EBT-101, involves using CRISPR-Cas9 gene editing to treat HIV. This potential treatment strategy has been studied in animal models since the development of CRISPR-Cas9 in 2012 ...

The gene-editing technique CRISPR disabled HIV that lay dormant in immune cells in a lab experiment, raising hopes for an eventual cure By Clare Wilson 19 March 2024 ...

Vaccine makers have also struggled because HIV kills the very immune cells meant to stop infection. But a decade ago, Khalili says, he realized that CRISPR might offer a way to cure the infection ...

When the enzyme encounters a target, such as a cancer-linked gene, it activates and begins shredding nearby DNA on the sensor ...

Initial research in Khalili’s lab showed that CRISPR could find and destroy the HIV genes in cells. The results were welcomed with caution by long-term survivors such as King. “Am I intrigued?

In the current study, the researchers inactivated mannosyl oligosaccharide glucosidase (MOGS), a gene essential to viral protein glycosylation, using CRISPR-Cas9 in immune cells derived from patients ...

The mice were also infected with latent HIV-1. After just one CRISPR/Cas9 treatment, researchers successfully removed viral fragments of the infected human cells embedded in mouse tissues and organs.

In July, an HIV-positive man became the first volunteer in a clinical trial aimed at using Crispr gene editing to snip the AIDS-causing virus out of his cells. For an hour, he was hooked up to an ...