The EMBO Journal1d
A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
AI-based tissue staining can detect amyloid deposits without chemical stains or polarization microscopy
Researchers at the University of California, Los Angeles (UCLA) have pioneered a groundbreaking approach in the imaging and ...
The EMBO Journal4d
RNF144B negatively regulates antiviral immunity by targeting MDA5 for autophagic degradation
MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
BMJ3d
Low-ratio somatic NLRC4 mutation causes late-onset autoinflammatory disease
We used single-cell RNA sequencing (scRNA-seq), intracellular cytokine staining, quantitative PCR, immunohistochemistry and western blotting to define inflammatory signatures and to explore the ...
disney.fandom6d
Toy Story 3 (Circle 7 Screenplay)
As the Circle 7 Toy Story 3 was further into production than the studio's other films, a greater volume of material corresponding to the film (such as concept art, character designs and a brief ...