Ensuring protein drugs are stable is a complex challenge. To be successful, formulation developers need to think beyond the molecule and also consider how the finished product will be handled after it ...

Solubility is fundamental in successfully developing all classes of therapeutic biopolymers. Contact with stressors related to mechanical stirring or changes in buffer conditions may cause ...

Formulation scientists are behind the conversion of active pharmaceutical ingredients (API) into stable, bioavailable, and commercially viable dosage forms, rarely a simple process. Image Credit: ...

To optimize the final formulation for a drug, it must meet many criteria beyond producing a safe and effective product. For example, it must be stable and amenable to various manufacturing steps, such ...

Early on, the drug substance (DS) manufacturer will provide a wealth of preliminary characterization data. And if the drug is active in early nonclinical and preclinical testing, a larger quantity of ...

Stability is a critical factor in drug formulation, with implications for product quality, lifecycle management, and ...