This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

Mo Khalil is the Hok Lam and Kathleen Kam Wong Professor of Bioengineering and Professor of Molecular and Cellular Biology at the Harvard John A. Paulson School of Engineering and Applied Sciences ...

David Toews works for Pennsylvania State University. He receives funding from The National Science Foundation. People typically think about evolution as a linear process where, within a species, the ...

Important, previously unrecognized genetic changes common to all ancient and modern Homo sapiens spread in Africa more than 300,000 years ago, a new study finds. After that, the same investigation ...

Humans were isolated in southern Africa for about 100,000 years, which caused them to "fall outside the range of genetic variation" seen in modern-day people, a new genetic study reveals. The finding ...

ABSTRACT: Multi-objective optimization remains a significant and realistic problem in engineering. A trade-off among conflicting objectives subject to equality and inequality constraints is known as ...

The original version of this story appeared in Quanta Magazine. Imagine a town with two widget merchants. Customers prefer cheaper widgets, so the merchants must compete to set the lowest price.

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The accurate treatment of many-unpaired-electron systems remains a central challenge ...

The original version of this story appeared in Quanta Magazine. If you want to solve a tricky problem, it often helps to get organized. You might, for example, break the problem into pieces and tackle ...

An international team led by the Clínic-IDIBAPS-UB along with the Institute of Cancer Research, London, has developed a new method based on DNA methylation to decipher the origin and evolution of ...

Scientists have uncovered new evidence suggesting that autism may have it roots in how the human brain has evolved. "Our results suggest that some of the same genetic changes that make the human brain ...