A pyrogen is defined as a substance that produces a rise in temperature in a human or animal, and pyrogens are categorized into exogenous pyrogens, which induce fever after parenteral …

pyrogen Any substance that causes fever. Endogenous pyrogens are proteins, such as interleukin-1, released by white blood cells in response to bacterial or viral infections.

Fever is a highly significant indicator of disease. …system’s responses is to produce pyrogens. These chemicals are carried by the blood to the brain, where they disturb the functioning of the …

The meaning of PYROGEN is a fever-producing substance.

Pyrogens are substances that cause a rise in body temperature, leading to what is commonly known as a fever. These compounds signal the body to elevate its internal thermostat, a …

Nov 9, 2025 · A pyrogen is defined as any substance that causes a fever when it enters the bloodstream, triggering a systemic inflammatory response. Testing products like injectable …

Pyrogens are substances that cause an increase in body temperature by triggering the hypothalamus to elevate the body's set point. They can be exogenous, originating from …

Pyrogen is a substance, either endogenous or exogenous, that has the ability to cause an increase in body temperature, resulting in fever and various systemic changes.

Jul 23, 2021 · The result is a condition called fever. The action of pyrogen resulting in a febrile response is thought to be a part of the body’s ability to combat infection. The increase in body …

Jul 22, 2025 · Endogenous pyrogens are substances produced within the body, primarily by immune cells. These proteins, such as interleukins (IL-1, IL-6) and tumor necrosis factor …