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EHA 2024 Insights: The Impact of TP53 Mutation Burden on Risk & Treatment Decision in Newly Diagnosed CLL
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When there is a mutation in TP53, damaged cells keep dividing, resulting in cancer #cancer #medical #mutation | Blooddocdad
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BTK Inhibitors in the Presence of 17p Deletions or TP53 Mutation in CLL | CancerNetwork
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🌾🌾Dr.Agrarian🌾🌾 on Instagram: "p53 is a crucial tumor suppressor gene located on chromosome 17p13.1 in humans and encodes a transcription factor that maintains genomic stability. Key features (short description) Gene name: TP53 Protein type: Sequence-specific DNA-binding transcription factor Major role: Acts as the “guardian of the genome.” Functions Cell-cycle arrest: Activated by DNA damage, hypoxia, or oncogene stress; induces p21 expression to stop the cell cycle at G1/S checkpoint. DNA
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🌾🌾Dr.Agrarian🌾🌾 on Instagram: "p53 is a crucial tumor suppressor gene located on chromosome 17p13.1 in humans and encodes a transcription factor that maintains genomic stability. Key features (short description) Gene name: TP53 Protein type: Sequence-specific DNA-binding transcription factor Major role: Acts as the “guardian of the genome.” Functions Cell-cycle arrest: Activated by DNA damage, hypoxia, or oncogene stress; induces p21 expression to stop the cell cycle at G1/S checkpoint. DNA
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