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Day 7 🧪 Welcome back to 30 Days of ASCP: Ratchet Study Tips 🤪🤏🏽 TRALI vs TACO will both have your patient in respiratory distress after a transfusion, but the WHY is completely different. TRALI is a lung injury caused by donor antibodies activating the recipient’s neutrophils in the lungs leading to acute hypoxia, fever, hypotension, and NON-cardiogenic pulmonary edema. No fluid overload, just straight lung inflammation. TACO is a fluid overload problem leading to hypertension, JVD, crackles
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